ainm Béarla:Mononucleotide β-Nicotinamide
Comhchiallaigh Bhéarla:BETA-NMN; Béite-NicotinAMIDEMONONÚILÉITÉIDÍD;BETA-NICOTINAMIDERIBOSEMONOPHOSPHATE;3-(aimínacarbóin)-1-(5-fosfónata-béite-D-ribofCeimiceachleabharúránóisil)piridiniam;B-NICITINNAMIDÉANÚCLAITÍD;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE5′fosfáit;NICOTINAMIDIRIBOTÍD
CAS:1094-61-7
foirmle mhóilíneach:C11H15N2O8P
Molecular weight:334.22
EINECS:214-136-5
Melting point:166 °C(dec.)
Dealramh: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Mononucleotide Nicotanamides ginte ag nicotinamide (Nam) faoi chatalaíoch Nampt (a protease in vivo), agus ansin gintear mononucleotides nicotinamide ag mononucleotides nicotinamide adenosine transferase chuig NAD+. Is bealach díreach é mononucleotide nicotinamide a fhorlíonadh NAD+. Is féidir le mononucleotídí nicotinamide feabhas suntasach a dhéanamh ar chumas deisiúcháin damáiste DNA i gcealla. Tá an éifeacht a bhaineann le dul in aois a aisiompú bainte amach ag Chemicalbook ar deireadh. Déanfar mononucleotídí nicotinamide a thiontú ina substaintí “nicotinamide adenine dinucleotide (NAD)” atá riachtanach do mheitibileacht fuinnimh sa chorp. I dturgnaimh luch, deimhníodh gur féidir le mononucleotide nicotinamide géine ar a dtugtar acetylase a ghníomhachtú sa chorp, ionas go mbeidh ról aige chun an saol a shíneadh agus a chóireáil diaibéiteas. Is substaint é NAD is féidir leis an gcorp daonna a tháirgeadh. Tá sé deimhnithe ag taighde go laghdóidh ábhar NAD sa chorp de réir mar a thagann méadú ar aois.
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