Enskt nafn:β-Nicotinamide Einkirni
Ensk samheiti:BETA-NMN;BETA-NIKOTÍNAMÍÐMÓNÚKLEÓTÍÐ;BETA-NIKÓTÍNAMÍÐRIBÓSEMÓFOSFAT;3-(amínókarbónýl)-1-(5-O-fosfónató-beta-D-rífEfnabókúranósýl)pýridín;B-NIKÓTÍNAMÍÐMÓNÚKLEÓTÍÐ;NMN;NIKOTÍNAMÍÐ-1-IUM-1-BETA-D-RIBOFURANOSIDE5'FOSFAT;NIKOTÍNAMÍDERÍBÓTÍÐ
CAS:1094-61-7
Sameindaformúla:C11H15N2O8P
Molecular weight:334.22
EINECS:214-136-5
Melting point:166 °C(dec.)
Útlit: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Nikótínamíð einkirnis eru mynduð með nikótínamíði (Nam) undir hvatningu Nampt (próteasa in vivo), og síðan myndast nikótínamíð einkirningar með nikótínamíð einkirningum adenósín transferasa til NAD+. Nikótínamíð einkirningi er bein leið til að bæta við NAD+. Nikótínamíð einkirni geta verulega bætt viðgerðargetu DNA skemmda í frumum. Chemicalbook hefur loksins náð þeim áhrifum að snúa við öldrun. Nikótínamíð einkirningi verður breytt í „níkótínamíð adeníndínúkleótíð (NAD)“ efni sem eru nauðsynleg fyrir orkuefnaskipti í líkamanum. Í músatilraunum var staðfest að nikótínamíð einkirni getur virkjað gen sem kallast asetýlasi í líkamanum, til að gegna hlutverki í að lengja líf og meðhöndla sykursýki. NAD er efni sem mannslíkaminn getur framleitt. Rannsóknir hafa staðfest að innihald NAD í líkamanum mun minnka með hækkandi aldri.
beta nicotinamide
cas 1094 61 7
β nicotinamide mononucleotide
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