Lub npe Askiv:β-Nicotinamide Mononucleotide
English synonyms:BETA-NMNBETA-NICOTINAMIDEMONONUCLEOTIDE;BETA-NICOTINAMIDERIBOSEMONOPHOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofChemicalbookuranosyl)pyridinium;B-NICOTINAMIDEMONONUCLEOTIDE;NMNNICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE5'PHOSPHATE; NICOTINAMIDERIBOTIDE
CAS:1094-61-7
Molecular formula:C11H15N2O8P
Molecular weight：334.22
EINECS：214-136-5
Melting point：166 °C(dec.)
Qhov tsos: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Nicotinamide mononucleotides yog tsim los ntawm nicotinamide (Nam) nyob rau hauv lub catalysis ntawm Nampt (ib tug protease nyob rau hauv vivo), thiab ces nicotinamide mononucleotides yog generated los ntawm nicotinamide mononucleotides adenosine transferase rau NAD+. Nicotinamide mononucleotide yog ib txoj hauv kev ncaj qha los ntxiv NAD+. Nicotinamide mononucleotides tuaj yeem txhim kho lub peev xwm kho DNA puas hauv hlwb. Chemicalbook thaum kawg tau ua tiav cov txiaj ntsig ntawm thim rov qab kev laus. Nicotinamide mononucleotides yuav hloov mus rau "nicotinamide adenine dinucleotide (NAD)" cov khoom tseem ceeb rau lub zog metabolism hauv lub cev. Hauv kev sim nas, nws tau lees paub tias nicotinamide mononucleotide tuaj yeem qhib cov noob hu ua acetylase hauv lub cev, txhawm rau ua lub luag haujlwm hauv kev ua neej ntev thiab kho ntshav qab zib. NAD yog ib yam khoom uas tuaj yeem tsim los ntawm tib neeg lub cev. Kev tshawb fawb tau lees paub tias cov ntsiab lus ntawm NAD hauv lub cev yuav txo qis nrog lub hnub nyoog nce.
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