β-Nicotinamide Mononucleotide,CAS 1094-61-7 ,NMN

Emglish jina:β-Nicotinamide Mononucleotide

Visawe vya Kiingereza:BETA-NMN;BETA-NICOTINAMIDEMONONUCLEOTIDE;BETA-NICOTINAMIDERIBOSEMONOPHOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofChemicalbookuranosyl)pyridinium;B-NICOTINAMIDEMONUCLEOTI;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE5′PHOSPHATE;NICOTINAMIDERIBOTIDE

CAS:1094-61-7

Fomula ya molekuli:C11H15N2O8P

Molecular weight：334.22

EINECS：214-136-5

Melting point：166 °C(dec.)

Mwonekano: White to yellowish, crystalline powder, no obvious odor.

Usage:In mammals, β- Nikotinamidi mononucleotides huzalishwa na nikotinamidi (Nam) chini ya kichocheo cha Nampt (protease in vivo), na kisha nikotinamidi mononucleotidi huzalishwa na nicotinamide mononucleotides adenosine transferase to NAD+. Nicotinamide mononucleotide ni njia ya moja kwa moja ya kuongeza NAD+. Nikotinamidi mononucleotidi inaweza kuboresha kwa kiasi kikubwa uwezo wa kutengeneza uharibifu wa DNA katika seli. Chemicalbook hatimaye imepata athari ya kurejesha kuzeeka. Nikotinamidi mononucleotidi itabadilishwa kuwa "nicotinamide adenine dinucleotide (NAD)" vitu muhimu kwa kimetaboliki ya nishati mwilini. Katika majaribio ya panya, ilithibitishwa kuwa nicotinamide mononucleotide inaweza kuamsha jeni inayoitwa asetilizi mwilini, ili kuchukua jukumu la kurefusha maisha na kutibu ugonjwa wa kisukari. NAD ni dutu ambayo inaweza kuzalishwa na mwili wa binadamu. Utafiti umethibitisha kwamba maudhui ya NAD katika mwili yatapungua kwa ongezeko la umri.