Ingelesezko izena:β-Nikotinamida mononukleotidoa
Ingelesezko sinonimoak:BETA-NMN;BETA-NIKOTINAMIDEMONONUKLEOTIDO;BETA-NICOTINAMIDERIBOSEOMONOFOSFATO;3-(aminokarbonil)-1-(5-O-fosfonato-beta-D-ribofChemicalbookuranosyl)piridinio;B-NICOTINAMIDEMONONUKLEOTIDO;NMN;NICOTINAMIDA-1-IUM-1-BETA-D-RIBOFURANOSIDE5′FOSFATO;NICOTINAMIDERIBOTIDO
CAS:1094-61-7
Formula molekularra:C11H15N2O8P
Molecular weight：334.22
EINECS：214-136-5
Melting point：166 °C(dec.)
Itxura: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Nikotinamida mononukleotidoas nikotinamidak (Nam) sortzen dira Nampt (proteasa in vivo) katalisaren pean, eta, ondoren, nikotinamida mononukleotidoak adenosina transferasaren bidez sortzen dira. NAD+. Nikotinamida mononukleotidoa osatzeko modu zuzena da NAD+. Nikotinamida mononukleotidoek DNAren kalteen konponketa gaitasuna nabarmen hobetu dezakete zeluletan. Chemicalbook-ek azkenean lortu du zahartzearen alderantzizko eragina. Nikotinamida mononukleotidoak "nikotinamida adenina dinukleotidoa (NAD)" substantzia bihurtuko dira gorputzeko energia-metabolismorako funtsezkoak. Saguaren esperimentuetan, nikotinamida mononukleotidoak gorputzean azetilasa izeneko genea aktibatu dezakeela baieztatu zen, bizitza luzatzeko eta diabetesa tratatzeko zeregina izateko. NAD giza gorputzak ekoitzi dezakeen substantzia bat da. Ikerketek baieztatu dute gorputzeko NADaren edukia murriztu egingo dela adinaren hazkundearekin.
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