b-nikotinamid mononukleotid, CAS 1094-61-7, NMN

Inglizcha nomi:b-nikotinamid mononukleotid

Inglizcha sinonimlar:BETA-NMN;BETA-NICOTINAMIDEMONONULEOTID;BETA-NICOTINAMIDERIBOSEMONOFOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofChemicalbookuranosil)piridinium;B-NICOTINAMIDEMONULEOTI;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSID5′phosphate;NICOTINAMIDERIBOTIDE

CAS:1094-61-7

Molekulyar formula:C11H15N2O8P

Molecular weight：334.22

EINECS：214-136-5

Melting point：166 °C(dec.)

Tashqi ko'rinishi: White to yellowish, crystalline powder, no obvious odor.

Usage:In mammals, β- Nikotinamid mononukleotids Nampt (in vivo proteaz) katalizi ostida nikotinamid (Nam) tomonidan hosil bo'ladi, so'ngra nikotinamid mononukleotidlar nikotinamid mononukleotidlar adenozin transferazasi tomonidan hosil bo'ladi. NAD+. Nikotinamid mononukleotid qo'shimchani to'g'ridan-to'g'ri yo'ldir NAD+. Nikotinamid mononukleotidlari hujayralardagi DNK shikastlanishini tiklash qobiliyatini sezilarli darajada yaxshilaydi. Chemicalbook nihoyat qarishni teskari ta'sirga erishdi. Nikotinamid mononukleotidlari tanadagi energiya almashinuvi uchun zarur bo'lgan "nikotinamid adenin dinukleotid (NAD)" moddalariga aylanadi. Sichqoncha tajribalarida nikotinamid mononukleotid organizmdagi asetilaza deb ataladigan genni faollashtirishi, hayotni uzaytirish va diabetni davolashda rol o'ynashi tasdiqlandi. NAD inson tanasi tomonidan ishlab chiqarilishi mumkin bo'lgan moddadir. Tadqiqotlar shuni tasdiqladiki, organizmdagi NAD tarkibi yosh oshgani sayin kamayib boradi.