Nom anglès:Mononucleòtid de β-nicotinamida
Sinònims anglesos:BETA-NMN;BETA-NICOTINAMIDEMONONUCLEOTIDE;BETA-NICOTINAMIDERIBOSEMONOFOSFAT;3-(aminocarbonil)-1-(5-O-fosfonato-beta-D-ribofChemicalbookuranosil)piridini;B-NICOTINAMIDEMONONUCLEOTIDE;NMN;NICOTINAMIDA-1-IUM-1-BETA-D-RIBOFURANOSIDE5′FOSFAT;NICOTINAMIDERIBOTIDA
CAS:1094-61-7
Fórmula molecular:C11H15N2O8P
Molecular weight：334.22
EINECS：214-136-5
Melting point：166 °C(dec.)
Aparença: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Mononucleòtid de nicotinamidas són generats per la nicotinamida (Nam) sota la catàlisi de Nampt (una proteasa in vivo), i després els mononucleòtids de nicotinamida són generats pels mononucleòtids de nicotinamida adenosina transferasa a NAD+. El mononucleòtid de nicotinamida és una forma directa de complementar NAD+. Els mononucleòtids de nicotinamida poden millorar significativament la capacitat de reparació del dany de l'ADN a les cèl·lules. Chemicalbook ha aconseguit finalment l'efecte de revertir l'envelliment. Els mononucleòtids de nicotinamida es convertiran en substàncies "nicotinamida adenina dinucleòtid (NAD)" essencials per al metabolisme energètic del cos. En experiments amb ratolins, es va confirmar que el mononucleòtid de nicotinamida pot activar un gen anomenat acetilasa al cos, per tal de tenir un paper en allargar la vida i tractar la diabetis. El NAD és una substància que pot ser produïda pel cos humà. La investigació ha confirmat que el contingut de NAD al cos disminuirà amb l'edat.
beta nicotinamide
cas 1094 61 7
β nicotinamide mononucleotide
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