Ngaran Inggris:β-Nicotinamide Mononucleotide
Sinonim Inggris:BETA-NMN;BETA-NICOTINAMIDEMONONUCLEOTIDE;BETA-NICOTINAMIDERIBOSEMONOPHOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofChemicalbookuranosyl)piridinium;B-NICOTINAMIDEMONONUCLEOTIDE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE5′PHOSPHATE;NICOTINAMIDERIBOTIDE
CAS:1094-61-7
Rumus molekul:C11H15N2O8P
Molecular weight:334.22
EINECS:214-136-5
Melting point:166 °C(dec.)
Penampilan: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Nikotinamide mononucleotides dihasilkeun ku nikotinamida (Nam) dina katalisis Nampt (protease in vivo), lajeng nikotinamida mononukleotida dihasilkeun ku nicotinamide mononucleotides adénosin transferase ka NAD+. Nicotinamide mononucleotide mangrupikeun cara langsung pikeun suplement NAD+. Mononukleotida nikotinamida tiasa sacara signifikan ningkatkeun kamampuan ngalereskeun karusakan DNA dina sél. Chemicalbook tungtungna ngahontal pangaruh ngabalikeun sepuh. Mononukleotida nikotinamide bakal dirobih janten "nicotinamide adenine dinucleotide (NAD)" zat anu penting pikeun métabolisme énérgi dina awak. Dina percobaan beurit, dikonfirmasi yén nicotinamide mononucleotide tiasa ngaktifkeun gén anu disebut acetylase dina awak, ku kituna maénkeun peran dina manjangkeun umur sareng ngubaran diabetes. NAD mangrupikeun zat anu tiasa diproduksi ku awak manusa. Panaliti parantos negeskeun yén eusi NAD dina awak bakal turun kalayan ningkat umur.
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