Angliškas pavadinimas:β-nikotinamido mononukleotidas
Anglų kalbos sinonimai:BETA-NMN;BETA-NIKOTINAMIDEMONONUKLEOTIDAS;BETA-NIKOTINAMIDERIBOSEMONOFOSFATAS;3-(aminokarbonil)-1-(5-O-fosfonato-beta-D-ribofChemicalbookuranosyl)piridinis;B-NIKOTINAMIDEMONONUKLEOTIDAS;NMNNIKOTINAMIDAS-1-IUM-1-BETA-D-RIBOFURANOZIDAS 5′FOSFATAS; NIKOTINAMIDEERIBOTIDAS
CAS:1094-61-7
Molekulinė formulė:C11H15N2O8P
Molecular weight:334.22
EINECS:214-136-5
Melting point:166 °C(dec.)
Išvaizda: White to yellowish, crystalline powder, no obvious odor.
Usage:In mammals, β- Nikotinamido mononukleotidass generuoja nikotinamidas (Nam), katalizuojamas Nampt (proteazė in vivo), o po to nikotinamido mononukleotidus generuoja nikotinamido mononukleotidai adenozino transferazė į NAD+. Nikotinamido mononukleotidas yra tiesioginis būdas papildyti NAD+. Nikotinamido mononukleotidai gali žymiai pagerinti ląstelių DNR pažeidimo gebėjimą atstatyti. Chemicalbook pagaliau pasiekė senėjimą stabdantį efektą. Nikotinamido mononukleotidai bus paverčiami "nikotinamido adenino dinukleotidu (NAD)" medžiagomis, būtinomis energijos apykaitai organizme. Eksperimentuose su pelėmis buvo patvirtinta, kad nikotinamido mononukleotidas organizme gali suaktyvinti geną, vadinamą acetilaze, taip prailginant gyvenimą ir gydant diabetą. NAD yra medžiaga, kurią gali gaminti žmogaus kūnas. Tyrimai patvirtino, kad NAD kiekis organizme mažės senstant.
beta nicotinamide
cas 1094 61 7
β nicotinamide mononucleotide
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