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bulk pharmaceutical intermediates

β-Nicotinamide Mononucleotide,CAS 1094-61-7 ,NMN

β-Nicotinamide Mononucleotide,CAS 1094-61-7 ,NMN
Emglish name:β-Nicotinamide Mononucleotide,CAS 1094-61-7 ,NMN

Taipitopito Hua

Tohu Hua

Ingoa English:β-Nicotinamide Mononucleotide

kupu taurite Ingarihi:BETA-NMN;BETA-NICOTINAMIDEMONONUCLEOTIDE;BETA-NICOTINAMIDERIBOSEMONOPHOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofChemicalbookuranosyl)pyridinium;B-NICOTINAMIDEMONONUCLEOTIDE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE5′PHOSPHATE;NICOTINAMIDERIBOTIDE

CAS:1094-61-7

tātai rāpoi:C11H15N2O8P

Molecular weight:334.22

EINECS:214-136-5

Melting point:166 °C(dec.)

Te ahua: White to yellowish, crystalline powder, no obvious odor.

Usage:In mammals, β- Nicotinamide mononucleotides ka hangaia e te nicotinamide (Nam) i raro i te catalysis o Nampt (he protease in vivo), katahi ka hangaia nga mononucleotides nicotinamide e te nicotinamide mononucleotides adenosine transferase ki NAD+. Ko te Nicotinamide mononucleotide he huarahi tika hei taapiri NAD+. Ka taea e Nicotinamide mononucleotides te whakapai ake i te kaha whakatikatika o te kino o te DNA i roto i nga pūtau. Kua tutuki i te Chemicalbook te hua o te huri i te koroheketanga. Ko te Nicotinamide mononucleotides ka huri hei "nicotinamide adenine dinucleotide (NAD)" nga matū e tika ana mo te whakawhitinga o te kaha o te tinana. I roto i nga whakamatautau kiore, i whakapumautia ka taea e te nicotinamide mononucleotide te whakahohe i tetahi ira e kiia nei ko te acetylase i roto i te tinana, kia whai waahi ai ki te whakaroa i te ora me te rongoa i te mate huka. Ko te NAD he matū ka taea e te tinana o te tangata te whakaputa. Kua whakapumautia e te rangahau ko te ihirangi o te NAD i roto i te tinana ka heke me te piki haere o te tau.

 

 

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