Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isoflurane

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isoflurane Manufacturers

Isoflurane, etere aloġenat intriganti li jippossjedi attributi anestetiċi notevoli, kien suġġett ta 'faxxinu xjentifiku. Filwaqt li l-intricacies kkomplikati tal-mekkaniżmi anestetiċi tal-isoflurane għadhom jaħarbu minn komprensjoni sħiħa, investigazzjonijiet reċenti dwar l-effetti tiegħu fuq il-ġrieden kixfu xi għarfien intriganti. Ġrieden mogħnija b'reżistenza inerenti għall-charms sedattivi ta 'isoflurane juru tnaqqis notevoli ta' 86% fl-espressjoni tal-ġene responsabbli għall-kodifikazzjoni tas-subunità tar-riċettur GABAA β1, b'kuntrast qawwi mal-kontropartijiet aktar suxxettibbli tagħhom. Din is-sejba partikolari tissuġġerixxi involviment plawżibbli tar-riċettur GABAA fl-orkestrazzjoni tal-influwenza ipnotika tal-isoflurane.

Fil-qasam tal-esperimentazzjoni murina, ġie nnutat li l-amministrazzjoni ta 'isoflurane f'konċentrazzjoni ta' 1.5% fuq medda ta '4 sigħat teżerċita impatt dixxernibbli fuq il-memorja ta' rikonoxximent spazjali. Evidentement, kemm fit-test tal-alternanza spontanja kif ukoll fl-enigmatiku Y-labirint, il-fakultajiet konjittivi tal-ġrieden jesperjenzaw indeboliment sussegwenti għall-espożizzjoni għall-isoflurane. Notevolment, dan l-indeboliment jibqa' persistenti għal tul minimu ta' 24 siegħa. B'mod notevoli, il-pajsaġġ molekulari jesperjenza wkoll alterazzjoni, peress li l-livelli ta 'Jnk1/2 fosforilati jirreġistraw elevazzjoni notevoli matul dan il-perjodu ta' żmien, u b'hekk iżid saff ieħor ta 'kumplessità għall-effetti ta' wara ta 'isoflurane.

L-applikazzjoni ta 'formulazzjonijiet infużi b'isoflurane stabbilixxiet preżenza notevoli fl-isfera ta' l-anestetiċi, u tat kredibilità għar-rilevanza u l-utilità dejjiema tagħha fil-prattika medika.

Sib Manifatturi u Fornituri ta 'Isoflurane fiċ-Ċina

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Qabbad ma 'manifatturi kwalifikati.

Informazzjoni Teknika

Isem kimiku: 1-chloro-2,2,2-trifluoroethyl difluoroethyl ether

Formula molekulari: c3h2clf5o

Piż molekulari: 184.49

Ċertifikat tal-GMP CFDA

Ħażna: -20°C

Tbaħħir: Temperatura tal-kamra fl-Istati Uniti kontinentali; jistgħu jvarjaw x'imkien ieħor

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