Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

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Isoflurane

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isoflurane, etherek halojenkirî ya balkêş ku xwedan taybetmendiyên anestezîkî yên berbiçav e, bûye mijara balkêşiya zanistî. Digel ku tevliheviyên tevlihev ên mekanîzmayên anestezîkî yên isoflurane berdewam dikin ku ji têgihîştina bêkêmasî dûr dikevin, lêkolînên vê dawiyê yên li ser bandorên wê li ser mişkan hin têgihîştinên balkêş eşkere kirin. Mişkên ku xwedan berxwedanek xwerû ya li hember dilşewatiyên aram ên isoflurane kêmbûnek berbiçav 86% di vegotina gena ku berpirsiyarê kodkirina binyekeya receptorê GABAA β1 de ye nîşan didin, berevajî hevpîşeyên wan ên pir metirsîdar. Vê vedîtina taybetî tevlêbûnek maqûl a receptorê GABAA di organîzekirina bandora hîpnotîk a isoflurane de destnîşan dike.

Di warê ceribandina mêşê de, hate destnîşankirin ku rêveberiya isoflurane bi giraniya 1.5% di navberek 4 demjimêran de bandorek berbiçav li ser bîranîna nasîna cîhê dike. Eşkere ye, hem di ceribandina veguheztina spontan û hem jî di mazîka Y-ya enigmatîk de, fakulteyên cognitive yên mişkan ji ber rûdana isoflurane kêmasiyekê dibînin. Nemaze, ev kêmasî bi domdarî herî kêm 24 demjimêran dom dike. Balkêş e, perestgeha molekulî di heman demê de guherînek jî çêdibe, ji ber ku astên Jnk1/2 fosforilated di vê heyamê de bilindbûnek berbiçav tomar dike, bi vî rengî qatek din a tevliheviyê li bandorên îsoflurane zêde dike.

Serîlêdana formulasyonên ku bi isoflurane ve hatî vegirtin di warê anesthetics de hebûnek berbiçav ava kiriye, ku pêbawerî û karanîna wê ya domdar di pratîka bijîjkî de dide.

Dîtina Hilberîner û Pêşkêşkerên Isoflurane li Chinaînê

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Bi çêkerên jêhatî re têkilî daynin.

Agahiya Teknîkî

Navê kîmyewî: 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether

Formula molekulî: c3h2clf5o

Giraniya molekulî: 184,49

Sertîfîkaya GMP CFDA

Hilanîn: -20°C

Şandina: Germahiya odeyê li parzemîna DY; dibe ku li cîhek din cûda bibe

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