Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isofluran

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isofluran Manufacturers

Isoflurane, suatu eter terhalogenasi menarik yang memiliki atribut anestesi terkenal, telah menjadi subjek daya tarik ilmiah. Meskipun seluk-beluk mekanisme anestesi isofluran masih belum dapat dipahami sepenuhnya, penyelidikan terbaru terhadap efeknya pada tikus telah mengungkap beberapa wawasan yang menarik. Tikus yang memiliki ketahanan terhadap obat penenang isofluran menunjukkan penurunan ekspresi gen yang bertanggung jawab untuk mengkode subunit reseptor GABAA β1 sebesar 86%, sangat berbeda dengan tikus yang lebih rentan. Temuan aneh ini menunjukkan kemungkinan keterlibatan reseptor GABAA dalam mengatur pengaruh hipnotis isofluran.

Dalam bidang eksperimen murine, telah diketahui bahwa pemberian isofluran pada konsentrasi 1,5% selama rentang waktu 4 jam memberikan dampak yang nyata pada memori pengenalan spasial. Terbukti, baik dalam tes pergantian spontan dan labirin Y yang penuh teka-teki, kemampuan kognitif tikus mengalami gangguan setelah terpapar isofluran. Khususnya, gangguan ini berlangsung terus-menerus selama minimal 24 jam. Hebatnya, lanskap molekuler juga mengalami perubahan, karena tingkat Jnk1/2 terfosforilasi mencatat peningkatan yang nyata selama jangka waktu ini, sehingga menambah lapisan kompleksitas pada efek samping isofluran.

Penerapan formulasi yang mengandung isofluran telah menunjukkan kehadirannya yang penting dalam bidang anestesi, sehingga memberikan kepercayaan terhadap relevansi dan kegunaannya dalam praktik medis.

Menemukan Produsen dan Pemasok Isoflurane di Cina

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Terhubung dengan produsen yang memenuhi syarat.

Informasi Teknis

Nama kimia: 1-kloro-2,2,2-trifluoroetil difluorometil eter

Rumus molekul: c3h2clf5o

Berat molekul: 184,49

CFDA sertifikat GMP

Penyimpanan: -20°C

Pengiriman: Suhu Kamar di benua AS; mungkin berbeda di tempat lain

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