Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

izofluran

izofluran

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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izofluran Manufacturers

Izofluran, zanimiv halogeniran eter z opaznimi anestetičnimi lastnostmi, je bil predmet znanstvene fascinacije. Medtem ko se zapletene zapletenosti anestetičnih mehanizmov izoflurana še vedno izmikajo popolnemu razumevanju, so nedavne raziskave njegovih učinkov na miši razkrile nekaj zanimivih spoznanj. Miši, obdarjene z inherentno odpornostjo na sedative čare izoflurana, kažejo izjemno 86-odstotno zmanjšanje izražanja gena, ki je odgovoren za kodiranje GABAA receptorske podenote β1, v popolnem nasprotju z njihovimi bolj dovzetnimi dvojniki. Ta nenavadna ugotovitev kaže na verjetno vpletenost receptorja GABAA pri orkestriranju hipnotičnega vpliva izoflurana.

Na področju eksperimentiranja z mišmi je bilo ugotovljeno, da dajanje izoflurana v koncentraciji 1,5 % v razponu 4 ur opazno vpliva na spomin za prostorsko prepoznavanje. Očitno je tako v spontanem alternacijskem testu kot v enigmatičnem Y-labirintu prišlo do poslabšanja kognitivnih sposobnosti miši po izpostavljenosti izofluranu. Predvsem ta okvara vztrajno traja najmanj 24 ur. Zanimivo je, da se spremeni tudi molekularna pokrajina, saj ravni fosforiliranega Jnk1/2 v tem časovnem okviru zabeležijo opazen dvig, s čimer dodajo še eno plast kompleksnosti posledicam izoflurana.

Uporaba formulacij, infundiranih z izofluranom, je vzpostavila omembe vredno prisotnost na področju anestetikov, kar daje verodostojnost njenemu trajnemu pomenu in uporabnosti v medicinski praksi.

Iskanje proizvajalcev in dobaviteljev izoflurana na Kitajskem

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Povežite se s kvalificiranimi proizvajalci.

Tehnične informacije

Kemijsko ime: 1-kloro-2,2,2-trifluoroetil difluorometil eter

Molekulska formula: c3h2clf5o

Molekulska masa: 184,49

GMP certifikat CFDA

Shranjevanje: -20°C

Dostava: sobna temperatura v celinskih ZDA; se lahko drugje razlikujejo

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