Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isofluran

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isofluran, en spennende halogenert eter som har bemerkelsesverdige anestetiske egenskaper, har vært gjenstand for vitenskapelig fascinasjon. Mens de intrikate forviklingene ved isofluranens bedøvelsesmekanismer fortsetter å unngå fullstendig forståelse, har nyere undersøkelser av effekten på mus avslørt noen spennende innsikter. Mus som er utstyrt med en iboende motstand mot den beroligende sjarmen til isofluran viser en bemerkelsesverdig 86 % reduksjon i uttrykket av genet som er ansvarlig for å kode for GABAA-reseptorunderenheten β1, i sterk kontrast til deres mer mottakelige motstykker. Dette særegne funnet antyder en plausibel involvering av GABAA-reseptoren i orkestreringen av isoflurans hypnotiske påvirkning.

Innenfor murine eksperimentering har det blitt oppdaget at administrering av isofluran i en konsentrasjon på 1,5 % over et tidsrom på 4 timer har en merkbar innvirkning på romlig gjenkjenningshukommelse. Tydeligvis, både i den spontane vekslingstesten og den gåtefulle Y-labyrinten, opplever de kognitive evnene til musene svekkelse etter eksponering for isofluran. Spesielt vedvarer denne svekkelsen vedvarende i en minimumsvarighet på 24 timer. Bemerkelsesverdig nok opplever det molekylære landskapet også endring, ettersom nivåer av fosforylert Jnk1/2 registrerer en merkbar økning i løpet av denne tidsrammen, og legger dermed enda et lag av kompleksitet til ettervirkningene av isofluran.

Anvendelsen av formuleringer infundert med isofluran har etablert en bemerkelsesverdig tilstedeværelse innen anestetika, og gir troverdighet til dens varige relevans og nytte i medisinsk praksis.

Finne isofluranprodusenter og -leverandører i Kina

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Ta kontakt med kvalifiserte produsenter.

Teknisk informasjon

Kjemisk navn: 1-klor-2,2,2-trifluoretyldifluormetyleter

Molekylformel: c3h2clf5o

Molekylvekt: 184,49

GMP-sertifikat CFDA

Oppbevaring: -20°C

Frakt: Romtemperatur i det kontinentale USA; kan variere andre steder

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