Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

isoflurano

isoflurano

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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El isoflurano, un intrigante éter halogenado que posee notables atributos anestésicos, ha sido objeto de fascinación científica. Si bien las complejidades de los mecanismos anestésicos del isoflurano continúan eludiendo una comprensión completa, investigaciones recientes sobre sus efectos en ratones han revelado algunas ideas intrigantes. Los ratones dotados de una resistencia inherente a los efectos sedantes del isoflurano muestran una notable reducción del 86% en la expresión del gen responsable de codificar la subunidad β1 del receptor GABAA, en marcado contraste con sus homólogos más susceptibles. Este hallazgo peculiar sugiere una posible participación del receptor GABAA en la orquestación de la influencia hipnótica del isoflurano.

En el ámbito de la experimentación murina, se ha descubierto que la administración de isoflurano a una concentración del 1,5% durante un lapso de 4 horas ejerce un impacto perceptible en la memoria de reconocimiento espacial. Evidentemente, tanto en la prueba de alternancia espontánea como en el enigmático laberinto en Y, las facultades cognitivas de los ratones experimentan un deterioro tras la exposición al isoflurano. En particular, este deterioro persiste de forma persistente durante un mínimo de 24 horas. Sorprendentemente, el paisaje molecular también experimenta alteración, ya que los niveles de Jnk1/2 fosforilado registran una elevación notable durante este período de tiempo, añadiendo así otra capa de complejidad a los efectos secundarios del isoflurano.

La aplicación de formulaciones con isoflurano ha establecido una presencia notable en el ámbito de los anestésicos, dando crédito a su perdurable relevancia y utilidad en la práctica médica.

Encontrar fabricantes y proveedores de isoflurano en China

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Conéctese con fabricantes calificados.

Información técnica

Nombre químico: éter 1-cloro-2,2,2-trifluoroetil difluorometilo

Fórmula molecular: c3h2clf5o

Peso molecular: 184,49

Certificado GMP CFDA

Almacenamiento: -20°C

Envío: Temperatura ambiente en EE. UU. continental; puede variar en otros lugares

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