Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Izoflurāns

Izoflurāns

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Izoflurāns, intriģējošs halogenēts ēteris, kam piemīt ievērojamas anestēzijas īpašības, ir bijis zinātnes aizraušanās objekts. Lai gan izoflurāna anestēzijas mehānismu sarežģītās sarežģītības turpina izvairīties no pilnīgas izpratnes, nesenie pētījumi par tā ietekmi uz pelēm ir atklājuši dažas intriģējošas atziņas. Pelēm, kurām ir raksturīga izturība pret izoflurāna sedatīvo pievilcību, ir ievērojams par 86% samazināts gēna ekspresija, kas ir atbildīga par GABAA receptoru apakšvienības β1 kodēšanu, kas ir krasā pretstatā to jutīgākajām partnerēm. Šis savdabīgais atklājums liecina par ticamu GABAA receptoru iesaistīšanos izoflurāna hipnotiskās ietekmes organizēšanā.

Peļu eksperimentu jomā ir konstatēts, ka izoflurāna ievadīšana 1,5% koncentrācijā 4 stundu laikā būtiski ietekmē telpiskās atpazīšanas atmiņu. Acīmredzot gan spontānās maiņas testā, gan mīklainajā Y-labirintā peļu kognitīvās spējas pēc izoflurāna iedarbības piedzīvo traucējumus. Jāatzīmē, ka šis traucējums pastāvīgi saglabājas vismaz 24 stundas. Jāatzīmē, ka arī molekulārā ainava piedzīvo izmaiņas, jo fosforilētā Jnk1/2 līmenis šajā laika posmā reģistrē ievērojamu paaugstināšanos, tādējādi izoflurāna sekām pievienojot vēl vienu sarežģītības slāni.

Ar izoflurānu infūziju saturošu zāļu formu pielietošana ir radījusi ievērojamu klātbūtni anestēzijas līdzekļu jomā, kas apliecina to pastāvīgo nozīmi un lietderību medicīnas praksē.

Izoflurāna ražotāju un piegādātāju atrašana Ķīnā

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Sazinieties ar kvalificētiem ražotājiem.

Tehniskā informācija

Ķīmiskais nosaukums: 1-hlor-2,2,2-trifluoretildifluormetilēteris

Molekulārā formula: c3h2clf5o

Molekulmasa: 184,49

GMP sertifikāts CFDA

Uzglabāšana: -20°C

Piegāde: istabas temperatūra kontinentālajā ASV; citur var atšķirties

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