Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isofluran

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isofluran, en spændende halogeneret æter med bemærkelsesværdige anæstetiske egenskaber, har været genstand for videnskabelig fascination. Mens de indviklede forviklinger af isofluran's bedøvelsesmekanismer fortsætter med at unddrage sig fuldstændig forståelse, har nylige undersøgelser af dets virkninger på mus afsløret nogle spændende indsigter. Mus, der er udstyret med en iboende resistens over for de beroligende charme af isofluran, viser en bemærkelsesværdig 86% reduktion i ekspressionen af genet, der er ansvarlig for at kode for GABAA-receptorunderenheden β1, i skarp kontrast til deres mere modtagelige modstykker. Dette ejendommelige fund tyder på en plausibel involvering af GABAA-receptoren i orkestreringen af isoflurans hypnotiske indflydelse.

Inden for murine eksperimenter er det blevet opdaget, at administration af isofluran i en koncentration på 1,5% over et tidsrum på 4 timer udøver en mærkbar indvirkning på rumlig genkendelseshukommelse. I både den spontane alterneringstest og den gådefulde Y-labyrint oplever musenes kognitive evner åbenbart svækkelse efter eksponering for isofluran. Det er bemærkelsesværdigt, at denne svækkelse fortsætter i en minimumsvarighed på 24 timer. Bemærkelsesværdigt oplever det molekylære landskab også ændringer, da niveauer af phosphoryleret Jnk1/2 registrerer en mærkbar stigning i løbet af denne tidsramme, og dermed tilføjer endnu et lag af kompleksitet til eftervirkningerne af isofluran.

Anvendelsen af formuleringer infunderet med isofluran har etableret en bemærkelsesværdig tilstedeværelse inden for anæstetika, hvilket giver troværdighed til dets vedvarende relevans og anvendelighed i medicinsk praksis.

At finde isofluran-producenter og -leverandører i Kina

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Forbind med kvalificerede producenter.

Teknisk information

Kemisk navn: 1-chlor-2,2,2-trifluorethyldifluormethylether

Molekylformel: c3h2clf5o

Molekylvægt: 184,49

GMP-certifikat CFDA

Opbevaring: -20°C

Forsendelse: Rumtemperatur i det kontinentale USA; kan variere andre steder

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