Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isofluraan

Isofluraan

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isofluraan Manufacturers

Isofluraan, intrigeeriv halogeenitud eeter, millel on märkimisväärsed anesteetilised omadused, on olnud teaduse huviorbiidis. Kuigi isofluraani anesteetikumide mehhanismide keerukus jääb endiselt täielikust mõistmisest kõrvale, on hiljutised uuringud selle mõju kohta hiirtele avaldanud mõningaid intrigeerivaid teadmisi. Hiirtel, kellel on loomupärane resistentsus isofluraani rahustavate võlude suhtes, väheneb GABAA retseptori subühikut β1 kodeeriva geeni ekspressioon märkimisväärselt 86%, mis on teravas vastuolus nende vastuvõtlikumate kolleegidega. See omapärane leid viitab GABAA retseptori usutavale osalemisele isofluraani hüpnootilise mõju korraldamisel.

Hiirekatsete valdkonnas on täheldatud, et isofluraani manustamine kontsentratsioonis 1,5% 4 tunni jooksul avaldab märgatavat mõju ruumilise tuvastamise mälule. Ilmselt kogevad nii spontaanse vaheldumise testi kui ka mõistatusliku Y-labürindi puhul pärast isofluraaniga kokkupuudet hiirte kognitiivsed võimed kahjustusi. Nimelt püsib see kahjustus püsivalt minimaalselt 24 tundi. Märkimisväärselt muutub ka molekulaarne maastik, kuna fosforüülitud Jnk1/2 tasemed registreerivad selle aja jooksul märgatava tõusu, lisades seega isofluraani järelmõjudele veel ühe keerukuse kihi.

Isofluraaniga infundeeritud preparaatide kasutamine on toonud esile tähelepanuväärse kohaloleku anesteetikumide valdkonnas, kinnitades selle püsivat tähtsust ja kasulikkust meditsiinipraktikas.

Isofluraani tootjate ja tarnijate leidmine Hiinast

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Võtke ühendust kvalifitseeritud tootjatega.

Tehniline informatsioon

Keemiline nimetus: 1-kloro-2,2,2-trifluoroetüüldifluorometüüleeter

Molekulaarvalem: c3h2clf5o

Molekulmass: 184,49

GMP sertifikaat CFDA

Säilitamine: -20°C

Kohaletoimetamine: toatemperatuur USA mandriosas; võib mujal erineda

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