Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isoflurane

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isoflurane Manufacturers

L'isoflurane, un éther halogéné intrigant possédant des attributs anesthésiques remarquables, suscite une fascination scientifique. Alors que les subtilités des mécanismes anesthésiques de l'isoflurane continuent d'échapper à une compréhension complète, des enquêtes récentes sur ses effets sur les souris ont dévoilé des informations intrigantes. Les souris dotées d'une résistance inhérente aux charmes sédatifs de l'isoflurane présentent une réduction remarquable de 86 % de l'expression du gène responsable du codage de la sous-unité β1 du récepteur GABAA, en contraste frappant avec leurs homologues plus sensibles. Cette découverte particulière suggère une implication plausible du récepteur GABAA dans l'orchestration de l'influence hypnotique de l'isoflurane.

Dans le domaine de l'expérimentation murine, il a été constaté que l'administration d'isoflurane à une concentration de 1,5 % sur une période de 4 heures exerce un impact perceptible sur la mémoire de reconnaissance spatiale. De toute évidence, tant dans le test d’alternance spontanée que dans l’énigmatique labyrinthe en Y, les facultés cognitives des souris subissent une altération suite à une exposition à l’isoflurane. Notamment, cette déficience persiste de manière persistante pendant une durée minimale de 24 heures. Remarquablement, le paysage moléculaire subit également une altération, car les niveaux de Jnk1/2 phosphorylés enregistrent une augmentation notable au cours de cette période, ajoutant ainsi une autre couche de complexité aux séquelles de l'isoflurane.

L'application de formulations infusées d'isoflurane a établi une présence remarquable dans le domaine des anesthésiques, donnant du crédit à sa pertinence et à son utilité durables dans la pratique médicale.

Trouver des fabricants et des fournisseurs d'isoflurane en Chine

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Connectez-vous avec des fabricants qualifiés.

Informations techniques

Nom chimique : 1-chloro-2,2,2-trifluoroéthyl difluorométhyléther

Formule moléculaire : c3h2clf5o

Poids moléculaire : 184,49

Certificat GMP CFDA

Stockage : -20°C

Expédition : température ambiante dans la zone continentale des États-Unis ; peut varier ailleurs

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