Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

izofluran

izofluran

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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izofluran Manufacturers

Izofluranul, un eter halogenat intrigant, care posedă atribute anestezice notabile, a fost un subiect de fascinație științifică. În timp ce complexitățile complicate ale mecanismelor anestezice ale izofluranului continuă să eludeze înțelegerea completă, investigațiile recente asupra efectelor sale asupra șoarecilor au dezvăluit câteva perspective interesante. Șoarecii înzestrați cu o rezistență inerentă la farmecele sedative ale izofluranului prezintă o reducere remarcabilă de 86% a expresiei genei responsabile de codificarea subunității receptorului GABAA β1, în contrast puternic cu omologii lor mai susceptibili. Această descoperire ciudată sugerează o implicare plauzibilă a receptorului GABAA în orchestrarea influenței hipnotice a izofluranului.

În domeniul experimentării murine, s-a constatat că administrarea de izofluran la o concentrație de 1,5% pe o perioadă de 4 ore exercită un impact vizibil asupra memoriei de recunoaștere spațială. Evident, atât în testul de alternanță spontană, cât și în enigmaticul labirint Y, facultățile cognitive ale șoarecilor suferă deteriorări ulterioare expunerii la izofluran. În special, această afectare persistă în mod persistent pentru o durată minimă de 24 de ore. În mod remarcabil, peisajul molecular suferă, de asemenea, modificări, deoarece nivelurile de Jnk1/2 fosforilat înregistrează o creștere vizibilă în acest interval de timp, adăugând astfel un alt strat de complexitate efectelor secundare ale izofluranului.

Aplicarea formulărilor infuzate cu izofluran a stabilit o prezență demnă de remarcat în domeniul anestezicelor, dând credibilitate relevanței și utilității sale de durată în practica medicală.

Găsirea producătorilor și furnizorilor de izofluran în China

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Conectați-vă cu producători calificați.

Informații tehnice

Denumire chimică: 1-clor-2,2,2-trifluoretil difluormetil eter

Formula moleculară: c3h2clf5o

Greutate moleculară: 184,49

Certificat GMP CFDA

Depozitare: -20°C

Livrare: temperatura camerei în SUA continentale; poate varia în altă parte

aerrane isoflurane

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isoflurane 250ml

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