Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Isoflurano

Isoflurano

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Isoflurano Manufacturers

O isoflurano, um intrigante éter halogenado que possui atributos anestésicos notáveis, tem sido objeto de fascínio científico. Embora as complexidades dos mecanismos anestésicos do isoflurano continuem a escapar à compreensão completa, investigações recentes sobre os seus efeitos em ratos revelaram alguns insights intrigantes. Ratos dotados de uma resistência inerente aos encantos sedativos do isoflurano apresentam uma redução notável de 86% na expressão do gene responsável pela codificação da subunidade β1 do receptor GABAA, em forte contraste com os seus homólogos mais susceptíveis. Este achado peculiar sugere um envolvimento plausível do receptor GABAA na orquestração da influência hipnótica do isoflurano.

No domínio da experimentação murina, verificou-se que a administração de isoflurano numa concentração de 1,5% durante um período de 4 horas exerce um impacto discernível na memória de reconhecimento espacial. Evidentemente, tanto no teste de alternância espontânea como no enigmático labirinto em Y, as faculdades cognitivas dos ratos sofrem prejuízos subsequentes à exposição ao isoflurano. Notavelmente, esta deficiência persiste persistentemente por um período mínimo de 24 horas. Notavelmente, a paisagem molecular também sofre alterações, à medida que os níveis de Jnk1/2 fosforilado registam uma elevação notável durante este período de tempo, adicionando assim outra camada de complexidade aos efeitos posteriores do isoflurano.

A aplicação de formulações infundidas com isoflurano estabeleceu uma presença notável no domínio dos anestésicos, dando credibilidade à sua relevância e utilidade duradouras na prática médica.

Encontrar fabricantes e fornecedores de isoflurano na China

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Conecte-se com fabricantes qualificados.

Informação técnica

Nome químico: éter 1-cloro-2,2,2-trifluoroetil difluorometílico

Fórmula molecular: c3h2clf5o

Peso molecular: 184,49

Certificado GMP CFDA

Armazenamento: -20°C

Envio: Temperatura ambiente nos EUA continentais; pode variar em outro lugar

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