Isoflurane is an inhaled anesthetic with the chemical name 2-chloro-2- (difluoromethoxy) -1,1,1-trifluoroethane and the molecular formula C3H2ClF5O. It is a colorless and transparent liquid, easily volatile, soluble in organic solvents but insoluble in water, with a relative density of 1.495-1.510, a distillation range of 47-50 ℃, and a refractive index of 1.2990-1.3005. This drug belongs to the isomer of Enflurane, which induces anesthesia and awakens quickly, and has little effect on myocardial contractility and liver and kidney function. It inhibits the central nervous system to produce anesthetic effects, making it suitable for inducing and maintaining general anesthesia, as well as for labor anesthesia. Blood pressure and respiratory status should be monitored during use, and contraindications include patients with a history of malignant hyperthermia and pregnant women (excluding cesarean section). Adverse reactions mainly include hypotension, respiratory depression, occasional laryngeal spasms or vomiting. The commonly used concentration of oxygen mixture in clinical practice is 0.5% -3%, and 1% -2.5% concentration is often used to maintain anesthesia.

Izofluranas

Izofluranas

Isoflurane Manufacturers, CP, USP, EP Isoflurane, GMP , ODMF, API and FDF, export to all over the world. Isoflurane CAS No. 26675-46-7, is an organic compound, which belongs to inhalation general anesthesia. It is clinically applicable to surgical anesthesia for patients with epilepsy, diabetes and bronchial asthma. It is a colorless and transparent liquid with a boiling point of 48.5 ℃ and a refractive index of 1.301. It is insoluble in water and needs to be stored in a cool, light shielded and sealed place

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Izofluranas Manufacturers

Izofluranas, intriguojantis halogenintas eteris, turintis žymių anestetikų savybių, buvo mokslo žavesio objektas. Nors izoflurano anestezijos mechanizmų sudėtingumas ir toliau neleidžia visiškai suprasti, neseniai atlikti jo poveikio pelėms tyrimai atskleidė keletą intriguojančių įžvalgų. Pelėms, kurioms būdingas atsparumas raminamiesiems izoflurano žavesiams, geno, atsakingo už GABAA receptorių subvieneto β1 kodavimą, ekspresija pastebimai sumažėja 86 %, o tai visiškai skiriasi nuo jautresnių jų kolegų. Šis ypatingas atradimas rodo, kad GABAA receptoriai yra tikėtini organizuojant izoflurano hipnotizuojančią įtaką.

Eksperimentų su pelėmis srityje buvo pastebėta, kad 1,5 % koncentracijos izoflurano skyrimas per 4 valandas daro pastebimą poveikį erdvinio atpažinimo atminčiai. Akivaizdu, kad tiek spontaniško kaitos testo, tiek mįslingo Y labirinto metu pelių pažinimo gebėjimai pablogėja po ekspozicijos izofluranu. Pažymėtina, kad šis sutrikimas išlieka mažiausiai 24 valandas. Pažymėtina, kad molekulinis kraštovaizdis taip pat keičiasi, nes fosforilinto Jnk1/2 lygis per šį laikotarpį pastebimai padidėja, todėl izoflurano pasekmės tampa dar sudėtingesnės.

Su izofluranu užpiltų formulių taikymas atskleidė, kad anestetikų sferoje yra verta dėmesio, o tai patvirtina jų ilgalaikę svarbą ir naudą medicinos praktikoje.

Izoflurano gamintojų ir tiekėjų paieška Kinijoje

Finding a trustful partner in our business is one of the biggest challenges and to overcome that challenge and to make one’s work/life easy in finding the trusted manufacturer and supplier of Isoflurane, one can visit the Pipelinepharma website which helps you in finding the trusted manufacturers and suppliers of Isoflurane. Kunxiangda is a leading supplier of Isoflurane in China, providing high quality products at the lowest price. Susisiekite su kvalifikuotais gamintojais.

Technine informacija

Cheminis pavadinimas: 1-chlor-2,2,2-trifluoretildifluormetileteris

Molekulinė formulė: c3h2clf5o

Molekulinė masė: 184,49

GMP sertifikatas CFDA

Sandėliavimas: -20°C

Pristatymas: Kambario temperatūra žemyninėje JAV dalyje; kitur gali skirtis

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