Tuairisgeul
Tha Olprinone na neach-dìon roghnach phosphodiesterase 3 (PDE3). Tha Olprinone air a chleachdadh mar àidseant cardiotonic le buaidhean inotropic agus vasodilating dearbhach. Thathas ag aithris gu bheil Olprinone a 'leasachadh microcirculation agus a' lughdachadh sèid. Bidh Olprinone gu tric air a chleachdadh gus toradh cridhe àrdachadh às deidh seach-rathad cardiopulmonary (CPB). Chaidh Olprinone a thoirt a-steach aig ìre 0.2 μg / kg / min nuair a thòisichear a’ cur a-mach à CPB. Tha Olprinone cuideachd air buaidhean làidir antioxidative agus anti-inflammatory a nochdadh ann an leòn sgamhain oxidative air a bhrosnachadh le meconium.
Fiosrachadh Teicnigeach:
Synonyms: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a) pyridin-6-il)-6-methyl-2-o; e1020;xo-,monohydrochloride,monohydrate;OLPRINONEHCL;
Teisteanas: teisteanas GMP, CFDA
Foirmle Molecular: C14H10N4O • HCl
Cuideam foirmle: 286.7
Purity: ≥98%
Cruthachadh (Iarr atharrachadh cruth)
Canonical SMILES: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Fiosrachadh mu sholarachadh is stòradh:
Stòradh: -20 ° C
Luingearachd: Teòthachd an t-seòmair ann am mòr-thìr na SA; faodaidh e bhith eadar-dhealaichte ann an àiteachan eile
Seasmhachd: ≥ 4 bliadhna
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