Whakaahuatanga
Ko te Olprinone he aukati phosphodiesterase 3 (PDE3) whiriwhiri. Ka whakamahia te Olprinone hei kaihoko cardiotonic me nga painga inotropic me te vasodilating pai. Kua korerohia te Olprinone ki te whakapai ake i te microcirculation me te whakaiti i te mumura. He maha nga wa ka whakamahia te Olprinone ki te whakanui ake i te putanga o te ngakau i muri i te paahitanga ngakau (CPB). I whakauruhia te Olprinone i te tere o te 0.2 μg / kg / min i te wa i timata ai te weaning mai i te CPB. Kua whakaatu hoki a Olprinone i nga paanga antioxidative me nga huanga anti-inflammatory i roto i te whara o te huhu oxidative meconium-induced.
Mōhiohio Hangarau:
kupu taurite: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a)piridin-6-yl)-6-methyl-2-o;e1020;xo-,monohydrochloride,monohydrate;OLPRINONEHCL;
Tiwhikete: Tiwhikete GMP, CFDA
Tātai rāpoi: C14H10N4O • HCl
Taumaha Tātai :286.7
Pure :≥98%
Whakatairanga(Tono huringa hangai)
NGĀ ATA KANAKA: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Nga korero tuku me te rokiroki:
Rokiroki: -20°C
Te Tukunga: Te Mamahana Rūma i roto i te whenua US; ka rereke pea ki etahi atu waahi
Te pumau: ≥ 4 tau
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