Beskrivelse
Olprinon er en selektiv fosfodiesterase 3 (PDE3) hemmer. Olprinon brukes som kardiotonisk middel med positive inotropiske og vasodilaterende effekter. Olprinon er rapportert å forbedre mikrosirkulasjonen og dempe betennelse. Olprinon brukes ofte for å øke hjertevolum etter kardiopulmonal bypass (CPB). Olprinon ble infundert med en hastighet på 0,2 μg/kg/min når avvenning fra CPB ble startet. Olprinon har også vist potente antioksidative og antiinflammatoriske effekter i den mekoniuminduserte oksidative lungeskaden.
Teknisk informasjon:
Synonymer: Olprinonhydroklorid-Loprinonhydroklorid;3-pyridinkarbonitril,1,2-dihydro-5-(imidazo(1,2-a)pyridin-6-yl)-6-metyl-2-o;e1020;xo-,monohydroklorid,monohydrat;OLPRINONEHCL;
Sertifikat: GMP-sertifikat, CFDA
Molekylformel: C14H10N4O • HCl
Formelvekt: 286,7
Renhet: ≥98 %
Formulering (Be om endring av formulering)
Kanoniske SMIL: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Informasjon om frakt og lagring:
Oppbevaring: -20°C
Frakt: Romtemperatur i det kontinentale USA; kan variere andre steder
Stabilitet: ≥ 4 år
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