Tavsif
Olprinon selektiv fosfodiesteraza 3 (PDE3) inhibitori hisoblanadi. Olprinon ijobiy inotrop va vazodilatatsion ta'sirga ega kardiotonik vosita sifatida ishlatiladi. Olprinon mikrosirkulyatsiyani yaxshilash va yallig'lanishni susaytirishi haqida xabar berilgan. Olprinon ko'pincha kardiopulmoner bypassdan (CPB) keyin yurak chiqishini oshirish uchun ishlatiladi. CPBdan sutdan ajratish boshlanganda olprinon 0,2 mkg/kg/min tezlikda kiritildi. Olprinon, shuningdek, o'pkaning mekonium bilan qo'zg'atilgan oksidlovchi shikastlanishida kuchli antioksidant va yallig'lanishga qarshi ta'sir ko'rsatdi.
Texnik ma'lumotlar:
Sinonimlar: Olprinonegidroxlorid-Loprinonhidroklorid;3-piridinkarbonitril,1,2-dihidro-5-(imidazo(1,2-a)piridin-6-il)-6-metil-2-o;e1020;xo-,monohidroxlorid,monogidrat;OLPRINONEHCL;
Sertifikat: GMP sertifikati, CFDA
Molekulyar formula: C14H10N4O • HCl
Formulaning vazni: 286.7
Soflik: ≥98%
Formulyatsiya (formulani o'zgartirishni so'rash)
Kanonik tabassumlar: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Yuk tashish va saqlash ma'lumotlari:
Saqlash: -20°C
Yuk tashish: AQSh kontinentalidagi xona harorati; boshqa joyda farq qilishi mumkin
Barqarorlik: ≥ 4 yil
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