Beskrywing
Olprinone is 'n selektiewe fosfodiesterase 3 (PDE3) inhibeerder. Olprinone word gebruik as kardiotoniese middel met positiewe inotropiese en vasodilaterende effekte. Olprinone is gerapporteer om mikrosirkulasie te verbeter en inflammasie te verswak. Olprinone word dikwels gebruik om kardiale omset te verhoog na kardiopulmonêre omleiding (CPB). Olprinoon is toegedien teen 'n dosis van 0.2 μg/kg/min toe speen vanaf CPB begin is. Olprinone het ook kragtige antioksidatiewe en anti-inflammatoriese effekte getoon in die mekonium-geïnduseerde oksidatiewe longbesering.
Tegniese informasie:
Sinonieme: Olprinoonhidrochloried-Loprinoonhidrochloried;3-piridienkarbonitril,1,2-dihidro-5-(imidaso(1,2-a)piridien-6-iel)-6-metiel-2-o;e1020;xo-,monohidrochloried,monohidraat;OLPRINONEHCL;
Sertifikaat: GMP-sertifikaat, CFDA
Molekulêre Formule: C14H10N4O • HCl
Formule Gewig: 286,7
Suiwerheid: ≥98%
Formulering (Versoek formuleringsverandering)
Kanoniese GLIMLAGE: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Gestuur- en bergingsinligting:
Berging: -20°C
Versending: Kamertemperatuur in kontinentale VSA; kan elders verskil
Stabiliteit: ≥ 4 jaar
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