Katerangan
Olprinone mangrupakeun selektif phosphodiesterase 3 (PDE3) inhibitor. Olprinone dianggo salaku agén cardiotonic kalayan pangaruh inotropik sareng vasodilating positip. Olprinone geus dilaporkeun pikeun ngaronjatkeun microcirculation na attenuate peradangan. Olprinone mindeng dipaké pikeun ngaronjatkeun kaluaran cardiac sanggeus cardiopulmonary bypass (CPB). Olprinone diinfuskan dengan laju 0,2 μg/kg/menit saat disapih dari CPB dimulai. Olprinone ogé parantos nunjukkeun épék antioksidatif sareng anti radang anu kuat dina tatu paru-paru oksidatif anu disababkeun ku meconium.
Inpormasi Téknis:
sinonim: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihidro-5-(imidazo(1,2-a) piridin-6-yl)-6-métil-2-o;e1020;xo-,monohidroklorida,monohidrat;OLPRINONEHCL;
Sertipikat: sertipikat GMP, CFDA
Formula Molekul: C14H10N4O • HCl
Rumus Beurat: 286,7
Purity: ≥98%
Formulasi (Paménta parobahan formulasi)
Seuri kanonik: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Émbaran Pangiriman & Panyimpenan:
Panyimpenan: -20°C
pengiriman barang: Suhu Kamar di buana AS; bisa rupa-rupa di tempat séjén
Stabilitas: ≥ 4 taun
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