Sharaxaada
Olprinone waa fosfodiesterase 3 (PDE3) horjooge door ah. Olprinone waxaa loo isticmaalaa sida wakiilka cardiotonic oo leh saameyn togan inotropic iyo vasodilating. Olprinone ayaa lagu soo warramey inay hagaajiso microcirculation oo ay yareyso bararka. Olprinone waxaa badanaa loo isticmaalaa si loo kordhiyo wax soo saarka wadnaha ka dib markii wadnaha sambabada (CPB). Olprinone waxaa lagu shubay xadiga 0.2 μg/kg/min markii naaska laga gooyay CPB la bilaabay. Olprinone waxa kale oo ay muujisay saamaynta antioxidative iyo anti-bararka ee meconium-ku-dhacday dhaawaca sambabada oksidatiga.
Macluumaadka Farsamada:
La mid ah: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a)pyridin-6-yl)-6-methyl-2-o;e1020;xo-,monohydrochloride, monohydrate;OLPRINONEHCL;
Shahaadada: Shahaadada GMP, CFDA
Qaacidada unugyada: C14H10N4O • HCl
Miisaanka Formula: 286.7
daahirnimo:≥98%
Qaabka (Codso qaabaynta beddelka)
Dhoola caddaynta: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Dhoofinta & Macluumaadka Kaydinta:
Kaydinta: -20°C
Raridda: Heerkulka qolka ee qaaradaha Maraykanka; meelo kale way ku kala duwanaan kartaa
Xasilooni: ≥ 4 sano
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