Tsanangudzo
Olprinone inosarudza phosphodiesterase 3 (PDE3) inhibitor. Olprinone inoshandiswa se cardiotonic agent ine yakanaka inotropic uye vasodilating madhara. Olprinone inonzi inovandudza microcirculation uye kuderedza kuzvimba. Olprinone inowanzoshandiswa kuwedzera kubuda kwemoyo mushure me cardiopulmonary bypass (CPB). Olprinone yakaiswa pamwero we0.2 μg/kg/min pakatanga kurumurwa kubva kuCPB. Olprinone yakaratidzawo yakasimba antioxidative uye anti-inflammatory effects mune meconium-induced oxidative lung kukuvara.
Information Information:
Mashoko anoreva zvakafanana: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a)pyridin-6-yl)-6-methyl-2-o;e1020;xo-,monohydrochloride,monohydrate;OLPRINONEHCL;
Chitupa: GMP chitupa, CFDA
Molecular Formula: C14H10N4O • HCl
Kurema: 286.7
Kuchena :≥98%
Kugadzira (Kumbira shanduko yekugadzira)
Canonical SMILES: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Kutumira & Kuchengeta Ruzivo:
Kuchengetedza: -20°C
Kutumira: Kamuri Tembiricha mukondinendi US; zvinogona kusiyana kumwewo
Kugadzikana: ≥ 4 makore
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