Description
Olprinone dia phosphodiesterase selective 3 (PDE3) inhibitor. Olprinone dia ampiasaina ho cardiotonic mpandraharaha manana inotropic tsara sy vasodilating vokany. Olprinone dia voalaza fa manatsara ny microcirculation ary manalefaka ny areti-maso. Ny olprinone dia matetika ampiasaina hampitomboana ny fivoahan'ny fo aorian'ny fidiran'ny cardiopulmonary (CPB). Ny olprinone dia nampidirina tamin'ny tahan'ny 0.2 μg / kg / min rehefa natomboka ny fampinonoana avy amin'ny CPB. Olprinone koa dia nampiseho fiantraikany mahery vaika antioxidative sy anti-inflammatoire amin'ny ratra amin'ny havokavoka vokatry ny meconium.
Fampahalalana ara-teknika:
mitovitovy: Olprinonehydrochloride-Loprinonehydrochloride;3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a)pyridina-6-yl)-6-methyl-2-o;e1020;xo-,monohydrochloride,monohydrate;OLPRINONEHCL;
Fanamarinana: taratasy fanamarinana GMP, CFDA
Formula molekiola: C14H10N4O • HCl
Lanja formula: 286.7
Fahadiovana: ≥98%
Famolavolana (Fangatahana fanovana formulation)
SMILES Canonical: CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl
Fampahafantarana fandefasana & fitahirizana:
Fitehirizana: -20°C
Fandefasana: Temperature efitra any amin'ny kaontinanta amerikana; mety miovaova any an-kafa
Filaminana: ≥ 4 taona
Vakio ny Vaovaontsika farany
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