Description

L'olprinone est un inhibiteur sélectif de la phosphodiestérase 3 (PDE3). L'olprinone est utilisée comme agent cardiotonique avec des effets inotropes et vasodilatateurs positifs. Il a été rapporté que l'olprinone améliore la microcirculation et atténue l'inflammation. L'olprinone est souvent utilisée pour augmenter le débit cardiaque après un pontage cardio-pulmonaire (CPB). L'olprinone a été perfusée à un débit de 0,2 µg/kg/min au début du sevrage du CPB. L'olprinone a également montré de puissants effets antioxydants et anti-inflammatoires dans les lésions pulmonaires oxydatives induites par le méconium.

Informations techniques:

Synonymes : Chlorhydrate d'olprinone-chlorhydrate de loprinone ; 3-pyridinecarbonitrile,1,2-dihydro-5-(imidazo(1,2-a)pyridin-6-yl)-6-méthyl-2-o;e1020;xo-,monochlorhydrate,monohydraté ;OLPRINONEHCL ;

Certificat : certificat GMP, CFDA

Formule moléculaire : C14H10N4O • HCl

Poids de la formule : 286,7

Pureté :≥98 %

Formulation (Demander un changement de formulation)

SOURIRES canoniques : CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl

Informations d'expédition et de stockage :

Stockage : -20°C

Expédition : température ambiante dans la zone continentale des États-Unis ; peut varier ailleurs

Stabilité : ≥ 4 ans

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